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Metabolism and Elimination Mitoxantrone is excreted in urine and feces as both unchanged drug or as inactive metabolites. In human research, eleven% and 25% in the dose were recovered in urine and feces, respectively, as possibly guardian drug or metabolite over the five-working day period of time subsequent drug administration.A ligature of ſi on
In Section A, members will acquire distinct doses and schedules of oral ABBV-744 tablet to determine safe dosing program. More individuals might be enrolled with the recognized monotherapy dosign program. In Section B, contributors will obtain oral ruxolitinib and ABBV-744 will likely be offered as "add-on" therapy. In Section C, participants will